."But these 'circadian clock' proteins acquire an entirely new function in the tumor cells upon hormonal therapy: they keep these cancer cells alive, despite treatment. This has never been seen before.", who had received three months of anti-hormonal therapy before their surgery. After which their tissue was examined at the DNA level.
The results of this study might raise questions if disturbances to the body’s circadian clock could increase the risk of therapy insensitivity in prostate cancer."There is no evidence to support this," said medical oncologist."The circadian rhythm in prostate tumor cells is no longer functional, and the proteins have taken on an entirely new role.
Source: Healthcare Press (healthcarepress.net)
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