A fecal microbiota transplant may lead to alterations in cognitive function.

Manipulating the gut microbiome through FMT can be considered a novel treatment for mental illnesses.

A few years ago, a controversial surgeon announced his decision to perform the first human head transplant. His decision caused a storm in the media. The head transplant raised several philosophical and ethical concerns. However, it seems that the most philosophical issue that arose was who is the owner of the new hybrid: the donor of the head or the body—in other words, whether the self andThe concept of"self" is an old unresolved issue in history.

The belief that the self is a mobile entity and can transfer between bodies and worlds has taken root even in contemporary people's minds. However, the concept of the soul has been modernized for today's individuals. The concept of mind uploading into a supercomputer to recreate oneself in cyberspace, or transferring one's mind to another person through a chipset, as depicted in movies and media, reflects ancient beliefs.

There is some limited evidence that organ transplantation may alter personality. Almost half of heart transplant recipients have claimed to experience changes in their cognition. Other organ transplant recipients, such as those who have received kidney and liver transplants, have also reported similar experiences.As mentioned above, the extent of the microbiome's effect on cognitive functions and personality is unclear.

The psychological changes during FMT have been studied in both animals and humans. These studies indicate that FMT could serve as a novel therapeutic intervention forRecently, it has been explored that patients with schizophrenia exhibit a significant difference in the microbes responsible for metabolizing tryptophan compared to those in normal individuals. This study indicates the mutual interplay between the microbiome and cognitive disorders.

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