35 years of channelling potassium ions

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Cloning of the Shaker protein had far-reaching effects in neuroscience.

Nerve impulses travel through cells as trains of electrical signals called action potentials, which arise from fast changes in voltage when ions move across the neuronal membrane.

The membrane-spanning ion-channel proteins that mediate this process have fascinated scientists for more than half a century, since their existence was first proposed. The channels not only select for their preferred ion type — sodium (Na

 

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If you have the blueprint, i.e. coding, the biochemical and physiological behaviour of the bichemical structure is also reproducible in the same reference system of natural laws.

mnystori

A previously-unknown mechanism for nucleic acids to gain toxicity to trigger cancers & neurodegenerative diseases such as ALS. Naked nucleic acids universally interact with most intrinsically-disordered proteins of ~40% human proteome to disrupt their roles in phase separation.

Got that beat. I've been channelling potassium ions for more than 61 years. My mother's been doing it darn near 85 years.

One would expect with a handle such as “nature” the content would be about the beauty all around but instead inglorious work, not understandable to the masses, well done! blunders nature PLOSBiology PLOSMedicine PLOSSynbio DefenseDep_FPS

Wish I could read that article, but there's an absolutely insane pay wall in front of it.

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