10 Best 'Supernatural' Quotes, Ranked

For Sam and Dean Winchester, the family business is anything but typical—rather than follow in their father's footsteps in a typical career, the two brothers battled paranormal forces in hit series Supernatural. It premiered in 2005 on the now-defunct WB, then moved to the CW, where it stayed. The show lasted 15 seasons, ending in 2020 with over 300 episodes, and tackled just about every supernatural being imaginable.

9 “You roll with a guy so many years, you start to think he’s always gonna be next to you. And then something happens and you realize the other chair has gone empty.” Harry, Season 9, Episode 15 "Thinman" While taking selfies in her locked bedroom, a teenage girl was killed by a mysterious figure caught in the background of her photos in “Thinman.

7 "Are you under the impression that family’s supposed to make you feel good, make you an apple pie, maybe? They’re supposed to make you miserable! That’s why they’re family!” Bobby, Season 4, Episode 22 "Lucifer Rising" The apocalypse came ever closer in Season 4 finale “Lucifer Rising,” and after a fight, Sam and Dean’s relationship was strained as they prepared to fight separately—and Sam felt Dean was better offer far away from him.

5 "Well, they weren't evil people, you know. A lot of them were good, just something happened to 'em. Something they couldn't control." Sam, Season 2, Episode 16, "Roadkill" In “Roadkill,” after swerving to avoid hitting a man in the middle of the road, a young couple’s car crashed. When the woman, Molly , came to, her husband was missing, and she flagged down the first car she saw for help—which just so happened to be Sam and Dean in their Impala.

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