at the age of 62 after suffering months of brain fog and anxiety.
“At the moment, there are no treatments available on the NHS that slow down the cognitive decline that we see in the disease we’ve only been able to manage symptoms. But there is hope of the horizon,” she said. Donanemab appeared to slow down the decline of cognitive function in the brain by 35 per cent compared with a placebo, according to a phase three clinical trial involving 1,182 people with early-stage disease.
The second of the Alzheimer’s Society’s most promising drugs, Lecanemab may also be available within two years. “We believe lecanemab, which gained approval in US in January, is likely to be available in around 18 months,” Catherine Mummery, head of novel therapeutics at University College London’s Dementia Research Centre, told“And donanemab is filing for full approval in the US now, and likely to file shortly after elsewhere including UK; so within the next 2 years is a possibility, she said, adding: “It is a guesstimate as the timeline ultimately will be down to [regulators] NICE and MHRA processes.
US regulators approved lecanemab in January, just two months after its promising phase-three trial data, but UK trials are yet to begin.
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