By Tarun Sai LomteJul 12 2023Reviewed by Benedette Cuffari, M.Sc. A recent study published in Clinical Infectious Diseases evaluates how the coronavirus disease 2019 pandemic impacted antibiotic use in healthcare facilities throughout South America.
Antibiotic resistance is a significant global public health threat, with antibiotic overuse being the leading cause of resistance. A recent report highlighted considerable increases in antibiotic-resistant infections throughout the COVID-19 pandemic. A comprehensive survey of HCFs was conducted to examine changes in practices over time. AU data were obtained from dispensing records.
Analyses were stratified by all antibodies, ceftriaxone, and those showing activity against methicillin-resistant Staphylococcus aureus or Pseudomonas aeruginosa. The impact of the COVID-19 pandemic on AU across HCFs was estimated from relative median differences between the two periods. Interrupted-time series analyses were performed to examine temporal changes in AU due to COVID-19.
Three facilities reported antibiotic shortages, with all HCFs experiencing shortages in healthcare personnel. Delays in antibiotic susceptibility testing increased in two facilities. The increased use of β-lactam antibiotics with anti-P. aeruginosa activity was observed in three HCFs, with one facility reporting lower usage, whereas ICUs in two facilities reported increased usage. The use of antibiotics with anti-MRSA activity increased in three HCFs and ICUs in one HCF.
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