and how worried we need to be about a real-world fungus epidemic:Naughty Dog [the game production company] were really interested in mycology and fungi in general and when they were close to production they drafted me in to give talks explaining that [their storyline] wasn’t too fanciful; that parasites can jump from one organism to another.
The fungal group that caused this, cordyceps, do go into plants and grain. There’s one called rye ergot. And when humans eat infected rye, they have psychotic episodes. It’s a good historical background to suggest that the Salem witch trials were caused by people eating infected rye. There’s lots of other documented cases, like St Anthony’s Fire, which occurred in Europe, and was an example of convulsive behaviour.
It’s very slow moving, but fungi are more related to humans than they are to plants, and what kills the fungus, kills you. We haven’t developed a good arsenal of cocktails, so it’s quite easy to kill bacteria because they're very different and the chemicals that kill them won’t kill you. It’s a little bit like trying to kill cancer in your body – the chemotherapy might kill you. So that’s the problem.
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