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The Mag - NUFC Daily Update for 16/08/22 -

Jim Robertson | Aug 16, 2022 09:28 am Jurgen Klopp is never slow in coming out with excuses when things go against him and his team. The Liverpool boss watching on as Darwin Nunez got himself sent off.

 

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Could widespread use of antiviral treatment curb the COVID-19 pandemic? A modeling study - BMC Infectious DiseasesBackground Despite the development of safe and effective vaccines, effective treatments for COVID-19 disease are still urgently needed. Several antiviral drugs have shown to be effective in reducing progression of COVID-19 disease. Methods In the present work, we use an agent-based mathematical model to assess the potential population impact of the use of antiviral treatments in four countries with different demographic structure and current levels of vaccination coverage: Kenya, Mexico, United States (US) and Belgium. We analyzed antiviral effects on reducing hospitalization and death, and potential antiviral effects on reducing transmission. For each country, we varied daily treatment initiation rate (DTIR) and antiviral effect in reducing transmission (AVT). Results Irrespective of location and AVT, widespread antiviral treatment of symptomatic adult infections (20% DTIR) prevented the majority of COVID-19 deaths, and recruiting 6% of all adult symptomatic infections daily reduced mortality by over 20% in all countries. Furthermore, our model projected that targeting antiviral treatment to the oldest age group (65 years old and older, DTIR of 20%) can prevent over 30% of deaths. Our results suggest that early antiviral treatment (as soon as possible after inception of infection) is needed to mitigate transmission, preventing 50% more infections compared to late treatment (started 3 to 5 days after symptoms onset). Our results highlight the synergistic effect of vaccination and antiviral treatment: as the vaccination rate increases, antivirals have a larger relative impact on population transmission. Finally, our model projects that even in highly vaccinated populations, adding antiviral treatment can be extremely helpful to mitigate COVID-19 deaths. Conclusions These results suggest that antiviral treatments can become a strategic tool that, in combination with vaccination, can significantly reduce COVID-19 hospitalizations and deaths and can help control SARS-Co
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Ferne McCann shares wedding update and says she 'manifested' fiancé Lorri HainesFerne McCann has given an update on her wedding plans during a Q and A on Instagram as the television personality talked location, dates and engagement party plans
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Heathrow Airport extends cap on passengers to end of OctoberIt means a daily limit on departing passengers will now apply until after the October half-term holidays.
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Update given on Preston Western Distributor worksEarlier progress on the Preston Western Distributor from above Pic: CJ Green Work on a major new road linking Preston and Fylde to the M55 motorway has move
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