By Dr. Sushama R. Chaphalkar, PhD.May 9 2024Reviewed by Susha Cheriyedath, M.Sc. In a New York-based, prospective birth-cohort study published in the journal Environment International, researchers investigated the potential association between maternal urinary concentrations of bisphenols and phthalates during pregnancy and child adiposity outcomes from birth to four years.
However, research on the association between exposure to these chemicals during pregnancy and child growth has yielded conflicting results, possibly due to differences in study populations and measurement timing during pregnancy. Additionally, newer substitutes for well-studied chemicals like bisphenol A and di-2-ethylhexyl phthalate have been understudied in this context.
Further, weight, height, and skinfold thickness were used as indicators of child adiposity and growth, applying international growth standards. Birthweight and child sex were obtained from health records. Weight-for-height z-scores were determined from the INTERGROWTH-21 standard. Measurements were taken at ages 1, 2, and 3-5 years. Infant weight change categories were constructed based on standard deviation score change from birth to one or two years. Growth acceleration was defined as >0.
Prenatal Body Mass Index Chemicals Childhood Obesity Children Creatinine Endocrine Inflammation Metabolites Oxidative Stress Phthalates Pregnancy Research Stress
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