Oral semaglutide shows promising results for type 2 diabetes in routine clinical settings

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Semaglutide,Type 2 Diabetes,Agonist

Semaglutide and its effects on glycemic control, body weight (BW), and tolerability in routine clinical practice.

By Vijay Kumar MalesuMay 28 2024Reviewed by Lily Ramsey, LLM In a recent study published in the Journal of Clinical Medicine , a group of researchers described the clinical characteristics of patients with type 2 diabetes initiating oral semaglutide and assessed its effects on glycemic control, body weight , and tolerability in routine clinical practice.

Its efficacy in glycemic control, BW reduction, and safety have been consistently demonstrated in the Peptide Innovation for Early Diabetes Treatment trials program, which includes ten randomized controlled trials involving 9,543 subjects with T2D. About the study The present study was conducted in two Italian university-based diabetes centers using data from the Metaclinic/Medical Technology and Diagnostic Applications electronic chart system.

Oral semaglutide was initiated with a 4-week dose-escalation regimen, starting at 3 mg, followed by 7 mg, and increasing to 14 mg if tolerated.

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