By Bhavna KavetiAug 31 2022Reviewed by Susha Cheriyedath, M.Sc. Proteins are organic macromolecules that participate in gene regulation and cell metabolism. Additionally, they serve as powerful biological shields in protecting the body’s immune system and homeostasis.
An article published in the journal Advances in Colloid and Interface Science discussed the recent progress in protein sensing and protein detection using nanocellulose as the biosensor. Additionally, nanocellulose was highlighted as a super biosensor for protein detection, protein sensing, and analysis of diverse polypeptides from body fluid and simulated body fluid. Ultimately, promising prospects, new opportunities, and approaches in biomedical governance were proposed.
Cellulose nanofibers , bacterial nanocelluloses , and cellulose nanocrystals are types of nanocelluloses, obtained from raw celluloses via mechanical or chemical approaches. The nanomaterials derived from nanocellulose have similar advantages as native nanocellulose, along with outstanding photonics, surface chemistry behavior, and colloidal performance.
Cellulose-based aligned assemblies consisting of nanofibrillated cellulose and exfoliated graphene were generated during the growth of graphene monolayers. These biomimetic composites showed good tensile strength. The biomimetic nanocomposites constructed by Linder et al. were derived from the native nanofibrillated cellulose, proteins, and exfoliated graphite. The protein molecules consisted of hydrophobic blocks linked to graphene and cellulose-binding block through genetic engineering.
Based on the performance of polymers, incorporation of polymer networks into bacterial nanocellulose-based nanostructures can modulate the physical and chemical properties. Additionally, controlling the amount of polysaccharides in the growth of the culture medium can also modulate the physical properties of nanocellulose.
Conclusion Overall, materials based on nanocellulose provide a suitable platform for protein sensing. Nanotechnology and green strategies facilitated the integration of nanocellulose into polymers, metal oxide, metals, carbon, and many more for their application in biosensors used in protein sensing and protein detection.
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