New subset of T cells may enhance cancer immunotherapy

May 28 2024University of Houston

While T-cell immunotherapy has revolutionized cancer treatment, there is still much to learn. Unfortunately, not all patients respond to these therapies, so a better understanding of the properties of engineered T cells is necessary to improve clinical responses. "Our results showed that a subset of T cells, labeled as CD8-fit T cells, are capable of high motility and serial killing, found uniquely in patients with clinical response," reports first author and recent UH graduate Ali Rezvan in Nature Cancer.

Chimeric antigen receptors T cells used for the treatment of B cell malignancies can identify T-cell subsets with superior clinical activity. Using infusion products of patients with large B cell lymphoma, we integrated functional profiling using TIMING with subcellular profiling and scRNA-seq to identify a signature of multifunctional CD8 T cells .

Source: Education Headlines (educationheadlines.net)

B Cell Cancer Treatment Cell Drugs Immune System Immunotherapy Lymphoma RNA RNA Sequencing T-Cell

United Kingdom Latest News, United Kingdom Headlines

Similar News:You can also read news stories similar to this one that we have collected from other news sources.

West Coast Conference adding Grand Canyon University, Seattle University in 2025GCU and Seattle will both compete in 14 of the WCC’s sponsored sports.
Source: The Athletic UK - 🏆 123. / 51 Read more »

Digital playtime can be good for children's well-being, finds new reportNew research from UNICEF Innocenti, produced in partnership with the University of Sheffield, New York University, City University New York and the Queensland University of Technology, explores the question of whether video games can contribute to the well-being of children, and if so, how? This research looked to the voices of the young, based on...
Source: medical_xpress - 🏆 101. / 51 Read more »

Leaders of Northwestern, UCLA, and Rutgers to Testify Before Congress on Campus ProtestsHouse Republicans have summoned the leaders of Northwestern University and Rutgers University to testify.
Source: TIME - 🏆 93. / 53 Read more »

Manchester Met university announces new chancellor to replace Peter MandelsonLord Mandelson will stand down next January
Source: MENnewsdesk - 🏆 23. / 69 Read more »

Over 100 university students arrested in New York in pro-Palestine protestsPro-Palestine protests at universities have been erupting across the US, with an estimated 1.000 people arrested across campuses.
Source: itvnews - 🏆 69. / 61 Read more »

Columbia university protestors arrested as New York police storm campusClashes broke out at the University of California, Los Angeles protest encampment.
Source: Metro Newspaper UK - 🏆 61. / 63 Read more »