New biomedical engineering innovation shows potential to transform trauma care and surgical practices

May 10 2024Chapman University Chapman University's Fowler School of Engineering Founding Dean and Professor, Andrew Lyon, is a member of this multidisciplinary, multi-university scientific research team developing platelet-like particles that integrate into the body's clotting pathways to stop hemorrhage. Sanika Pandit, an alumna of Chapman University, is also among the 15 authors in this research.

The team has engineered platelet-like particles capable of traveling through the bloodstream and then homing to the site of tissue damage, where they augment the clotting process and then support subsequent wound healing. The approach addresses an unmet clinical need in trauma care and surgical practice.

Ashley Brown, corresponding author on the study and an associate professor in the joint biomedical engineering program at North Carolina State University and the University of North Carolina at Chapel Hill, said, "In the mouse and pig models, healing rates were comparable in animals that received platelet transfusions and synthetic platelet transfusions and both groups fared better than animals that did not receive either transfusion.

Wound Wound Healing Bleeding Medicine Platelet Trauma

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