Mental health conditions could accelerate cardiovascular risk in young and middle-aged women

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Younger women are generally thought to have a low risk of heart disease, but new research urges clinicians to revisit that assumption, especially for women who suffer from certain mental health conditions.

Mar 28 2024American College of Cardiology A new study being presented at the American College of Cardiology's Annual Scientific Session found that having anxiety or depression could accelerate the development of cardiovascular risk factors among young and middle-aged women.

We often feel that young women are the 'safe group' with regards to cardiovascular disease because the incidence of cardiovascular disease is quite low due to the protective effects of estrogen in this group. But this study suggests that if a younger woman has depression or anxiety, we should start screening for cardiovascular risk factors to reduce the incidence of cardiovascular disease.

During the 10-year follow-up period, 38% of participants developed high blood pressure, high cholesterol and/or diabetes. According to the analysis, those with a history of anxiety or depression before the study period were about 55% more likely to develop one or more of these risk factors than people without anxiety or depression.

To study the potential drivers behind this relationship, the researchers examined the metabolic activity of stress-related brain regions in a subset of participants who had undergone brain scans. The results indicated that younger women with anxiety or depression showed relatively large increases in stress-related neural activity.

 

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