after endovascular treatment is associated with greater disability in people who have had an acute ischemic stroke.
"There is always the concern if blood pressure is lowered too much in patients who are having an acute ischemic stroke that it could make the size of their stroke worse by reducing already compromised blood flow in that area," Mistry explained.and successful endovascular treatment at one of three urban comprehensive stroke centers between January 2020 and March 2022.
Patients were treated with a blood pressure medication called nicardipine, administered intravenously, started within one hour after endovascular treatment and given for 24 hours if theirwas above the target they were assigned. Researchers wanted to assess whether lowering blood pressure may cause harm to brain tissue, which is particularly vulnerable during the 24 hours after a stroke, and to assess disability 90 days later.
"Although the study did not find a significant evidence of an unequivocal harm of lower blood pressure targets in this population in terms of worsening size of stroke or increasing disability, the trends indicated that there may only be marginal benefit of lowering post-endovascular treatment blood pressure on patients' long-term disability," Mistry said.
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