Public health officials in Nottinghamshire have issued important advice over concerns of the prospect of a 'twindemic' - a combination of flu and Covid-19 which could put pressure on the NHS this winter. According to the Office for National Statistics, an estimated 1.1million people in private households tested positive for Covid, which covered the seven days up to September 17 in England, and up to September 30 in Wales, Scotland and Northern Ireland.
Read more: Nottinghamshire trust affected by 'higher than normal' emergency calls and Covid infections to take measures Amanda Sullivan, chief executive of NHS Nottingham and Nottinghamshire, said a spike in the number of Covid patients had been a contributory factor in the healthcare systems decision to declare a critical incident last week. She cited the fact that 243 people were in hospital with the virus on Wednesday, September 28.
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Voice Features of Sustained Phoneme as COVID-19 BiomarkerBackground: The COVID-19 pandemic has resulted in enormous costs to our society. Besides finding medicines to treat those infected by the virus, it is important to find effective and efficient strategies to prevent the spreading of the disease. One key factor to prevent transmission is to identify COVID-19 biomarkers that can be used to develop an efficient, accurate, noninvasive, and self-administered screening procedure. Several COVID-19 variants cause significant respiratory symptoms, and thus a voice signal may be a potential biomarker for COVID-19 infection. Aim: This study investigated the effectiveness of different phonemes and a range of voice features in differentiating people infected by COVID-19 with respiratory tract symptoms. Method: This cross-sectional, longitudinal study recorded six phonemes (i.e., /a/, /e/, /i/, /o/, /u/, and /m/) from 40 COVID-19 patients and 48 healthy subjects for 22 days. The signal features were obtained for the recordings, which were statistically analyzed and classified using Support Vector Machine (SVM). Results: The statistical analysis and SVM classification show that the voice features related to the vocal tract filtering (e.g., MFCC, VTL, and formants) and the stability of the respiratory muscles and lung volume (Intensity-SD) were the most sensitive to voice change due to COVID-19. The result also shows that the features extracted from the vowel /i/ during the first 3 days after admittance to the hospital were the most effective. The SVM classification accuracy with 18 ranked features extracted from /i/ was 93.5% (with F1 score of 94.3%). Conclusion: A measurable difference exists between the voices of people with COVID-19 and healthy people, and the phoneme /i/ shows the most pronounced difference. This supports the potential for using computerized voice analysis to detect the disease and consider it a biomarker.
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