Entorhinal grid-like codes and time-locked network dynamics track others navigating through space - Nature Communications

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Entorhinal grid-like codes and time-locked network dynamics: How we navigate through crowds NatureComms

. Omer and colleagues dissociated signals by either presenting another individual or an object moving through space while the observer bat remained stationary. A similar task design might be helpful to resolve this issue in follow-up work with humans. Hence, we cannot draw firm conclusions regarding the involvement of entorhinal grid-like coding specifically in socio-spatial navigation but consider our work an important first step in this direction.

To summarize, we found that grid-like codes in the human entorhinal cortex track other individuals that navigate through space. Grid signals during observation were tied to increases in co-activation and entorhinal-cortical connectivity with an ensemble of regions, including the striatum, hippocampus, parahippocampal and right posterior parietal cortices, altogether modulated by accuracy when subsequently re-tracing the paths.

The VR environment depicted a desert scene with landmarks and objects that were placed around a circular arena. The sandy ground was contrasted by a blue sky filled with clouds, while the sun was fixed at the circular arena’s zenith. The circular arena consisted of a movement area inside which the avatar and the participants could walk , as well as an observation area surrounding it (radius=90 vm, marked in white; Fig.

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physorg_com NatureComms Great Lord God will do miracles tomorrow in the sky. Be afraid of God.

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