Dolutegravir-based antiretroviral therapies for HIV-1 effective in pregnancy

, small for gestational age, or neonatal death) between dolutegravir-based regimens and the other contemporary regimens.

Dolutegravir, a more recently approved antiretroviral drug, is part of a once-a-day regimen that has been shown to be more effective, easier to tolerate, and less likely to create new drug resistance in people with HIV-1 compared with other. However, limited data have been available about its effectiveness and safety in pregnancy compared with regimens that commonly have been used during pregnancy in the U.S. and Europe.

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