Dietary fiber promotes beneficial conversion of tryptophan by gut bacteria

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Amino Acid,Colon,Diet

We get healthy dietary fibres from consuming fruits, vegetables, and whole grains. But why are the fibres so good for us? A team of researchers has discovered that dietary fibres play a crucial role in determining the balance between the production of healthy and harmful substances by influencing the behavior of bacteria in the colon.

Technical University of DenmarkJun 26 2024

"The gut bacterium E. coli can turn tryptophan into a harmful compound called indole, which is associated with the progression of chronic kidney disease. But another gut bacterium, C. sporogenes, turns tryptophan into healthy substances associated with protection against inflammatory bowel diseases, type 2 diabetes, cardiovascular diseases, and neurological diseases," says Anurag Kumar Sinha, a DTU National Food Institute researcher.

Understanding the behavior of gut bacteria It is well-known that dietary fibres can alter the composition and quantities of bacteria in our gut microbiome. However, looking merely at the composition and abundance of gut microbial species will not tell us much about their impact on our health.

Amino Acid Colon Diet E. Coli Food Large Intestine Metabolism Microbiology Microbiome Research Tryptophan Vegetables

 

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