Commonly used drug shows promise in managing symptoms of irritable bowel syndrome

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A recent study presented at UEG Week 2023 suggests that amitriptyline, a commonly used drug, can help manage symptoms of irritable bowel syndrome (IBS). IBS affects one in 20 people worldwide and currently has no cure. The study, funded by NIHR and conducted in primary care, found that patients who received amitriptyline experienced improvements in their symptoms compared to those who received a placebo.

A commonly used and widely available drug could help manage symptoms of irritable bowel syndrome in patients seen in GP surgeries, according to recent research.

The study was carried out by researchers from Universities of Leeds, Southampton, and Bristol and funded by the National Institute for Health and Care Research . Conducted in primary care, the research saw GPs prescribe the drop to IBS patients who managed their own dose based on the severity of their symptoms, using an adjustment document designed for the trial.

The researchers are now recommending that GPs use the drug to support patients with IBS, making the dose adjustment document widely available to medical professionals and patients.

 

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