Combined exercise and diet interventions show potential in improving ovarian cancer patients' outcomes

By Dr. Priyom Bose, Ph.D.May 13 2024Reviewed by Benedette Cuffari, M.Sc. A recent British Journal of Cancer study assesses whether a combined routine of exercise and dietary intervention improved fatigue, body composition, and physical functions in patients with ovarian cancer .

A typical treatment strategy for ovarian cancer is cytoreductive surgery followed by chemotherapy. After this treatment, patients often experience many physical and psychosocial problems, such as fatigue, reduced physical functioning, sarcopenia, and malnutrition, all of which significantly reduce their health-related quality of life .

Although some pilot studies have reported the benefits of moderate-intensity exercise interventions during chemotherapy in patients with ovarian cancer, a well-designed randomized controlled trial is needed to assess the effectiveness of a combined exercise and diet intervention approach in this patient population.

All study participants were evaluated at baseline , before the first or second chemotherapy cycle, and before randomization. Additionally, each study participant was assessed after the last cycle of chemotherapy and 12 weeks after T1 . The combined exercise and dietary intervention initiated at the first three-week cycle of chemotherapy continued until the last chemotherapy cycle.

The average age of the participants was 59 years, and 60% of the cohort received primary surgery followed by adjuvant chemotherapy treatment. There was no significant age difference between the intervention and control groups. The explorative analysis indicates that the efficacy of the combinational exercise and dietary intervention significantly depends on the level of adherence.

Source: Entertainment Trends (entertainmenttrends.net)

Exercise Ovarian Cancer Breast Cancer Chemotherapy Diet Efficacy Fatigue Malnutrition Physical Activity Sarcopenia Surgery

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