Clomiphene and dexamethasone boost fertility in PCOS patients

By Tarun Sai LomteMay 22 2024Reviewed by Susha Cheriyedath, M.Sc. In a recent study published in the journal BMC Women’s Health, researchers evaluated the efficacy of clomiphene and dexamethasone in treating polycystic ovary syndrome .

Study: A meta-analysis of efficacy on dexamethasone and clomiphene in the treatment of polycystic ovary syndrome patients. Image Credit: SewCreamStudio / Shutterstock Standardized mean differences and corresponding 95% confidence intervals were computed for continuous variables. Relative risk and corresponding 95% CIs were estimated for dichotomous variables. The I-squared statistic and the chi-squared test were performed to evaluate heterogeneity. Subgroup and sensitivity analyses were undertaken if there was substantial heterogeneity. Egger’s test, Begg’s test, and funnel plots were used to assess publication bias.

Analysis suggested that the combined treatment could improve the ovulation rate among PCOS patients. Ten studies reported LH levels, and heterogeneity was observed after data pooling. As such, a random-effects model was used; consistently, the combined treatment was likely to improve LH levels in PCOS patients.

Source: Healthcare Press (healthcarepress.net)

Fertility Efficacy Estradiol Estrogen Hormone Insulin Insulin Resistance Ovulation Polycystic Ovary Syndrome Pregnancy Syndrome Vertigo Vomiting

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