By Dr. Liji Thomas, MDJul 19 2022Reviewed by Benedette Cuffari, M.Sc. Although infection with the monkeypox virus is considered an endemic disease in certain African countries, it has now caused several outbreaks in multiple regions throughout the world. In a recent interview with the American Medical Association, scientists working with the United States Centers for Disease Control and Prevention provide the latest information about monkeypox in the U.S.
The current outbreak To date, over 600 probable and confirmed cases have been estimated across 47 U.S. states and territories. This indicates an actively spreading infection that is part of a worldwide outbreak that now includes over 10,600 confirmed cases in 65 countries. In response to this surge in cases, the CDC has made testing for the virus available at a number of commercial laboratories and is promoting greater testing for patients with symptoms suggestive of this disease.Symptoms Monkeypox is an orthopoxvirus like smallpox and vaccinia viruses that were used to create the smallpox vaccine. The symptoms of monkeypox infection are similar to those of smallpox; however, they are often milder and associated with a much lower death rate.
The scabbed lesions are often itchy, with some patients developing severe pain when the rashes first develop. Notably, the rash may arise before other symptoms in some patients. The clinical presentation of monkeypox may be similar to that of STIs like syphilis, herpes, lymph granuloma, venereum or other etiologies of proctitis.”
An untested monkeypox patient is an uncounted monkeypox patient and is someone who might be continuing to spread the virus.”For example, the CDC assay is being extended to five commercial laboratories, which is expected to increase testing capacity to 60,000 each week. Other laboratories are also setting up their own assays.
We need to be cognizant that these cases have probably been happening and this is our chance to detect them and then get prevention measures in place.” Vaccinia immune globulin The intravenous administration of vaccinia immune globulin is also approved for treating patients with complications arising from vaccinia infection and is being repurposed for monkeypox cases. The strategic national stockpile is sufficient to provide doses for the treatment of all patients who need it.
Presumed or close contacts are encouraged to take the vaccine pre-exposure in phases. It is not currently advised to vaccinate everyone, nor to vaccinate healthcare workers or laboratory staff unless they are involved in testing for this virus.
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