Antimicrobial-resistant hospital infections remain at least 12% above pre-pandemic levels, study finds

Antimicrobial-resistant hospital infections remain at least 12% above pre-pandemic levels, study findsDespite progress in combating antimicrobial resistance in the U.S. since its peak during the COVID-19 pandemic, hospital-acquired AMR infections remain well above pre-pandemic levels, according to a major new study examining AMR before, during, and after the COVID-19 pandemic in 120 US hospitals.

To provide an updated report on the status of AMR in US hospitals, researchers analyzed trends in incidence of AMR infections in adults in 120 hospitals before , during , and after the pandemic , that were continuously reporting in the PINC-AI database—an administrative dataset representing 20% of US hospitalizations.

During the pandemic, infections due to gram-negative pathogens—those that are resistant to multiple drugs and are increasingly resistant to most available antibiotics—increased by almost 20% compared to pre-pandemic levels, while resistant gram-positive infections fell by 4.2%. Interestingly, the researchers also found that hospitals with the highest levels of surges in severely ill COVID-19 patients during the pandemic had the largest increases in hospital-acquired AMR infections, with incidence increasing in a stepwise fashion. Larger hospitals with the highest bed capacity had more than double the odds of AMR infections compared to hospitals with the lowest bed capacity .

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