Debate over whether Americans should receive a booster dose of the Pfizer-BioNTech COVID-19 vaccine as planned by the Biden administration moved to a panel of independent expert advisers to the US Food and Drug Administration on Friday .
But US health officials planning the booster shot rollout are also eyeing rising COVID-19 cases. The highly transmissible Delta variant has caused a surge in hospitalizations and deaths, mostly among the unvaccinated, but less serious breakthrough infections among fully vaccinated people have also risen.
Pfizer's application to the FDA for a booster was for ages 16 and up, and the panel has been asked to weigh only one question: does the safety and effectiveness data support approval of a booster at least six months after the second dose for people aged 16 and older? "They're going to be in a difficult position, because I think most of them would believe that over 60 is justified and then under 60 is going to be a gray area," said John Moore, a professor of microbiology and immunology at Weill Cornell Medical College in New York, who has reviewed the presentations.
An analysis by Israeli scientists published on Wednesday found that among 1.1 million people age 60 or older who had been fully vaccinated at least five months earlier, those who received a booster were less likely to be infected or become severely ill than those who did not get the third shot.
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