The NTU team consisting of Associate Professor Hou Han Wei, research fellow Leong Sheng Yuan and research engineer Lok Wan Wei, with Associate Professor Rinkoo Dalan, from TTSH.Scientists in Singapore have developed a new method of isolating blood plasma that will allow for certain cancers and diseases, such as non-small cell lung cancer and Type 2 diabetes, to be detected more quickly and accurately.
The current method of isolating blood plasma by centrifugation involves multiple steps and can take up to an hour. Compared to other devices, this prototype is able to siphon biological particles that are smaller than a micron, which is about 100 to 200 times smaller than the diameter of a strand of human hair.
This collaboration allowed the team to test the clinical safety, effectiveness, and efficacy of the chip. Associate Professor Rinkoo Dalan, senior consultant specialising in diabetes and endocrinology at TTSH, said: “This technology can help clinicians better predict and manage complications of chronic metabolic conditions like diabetes, by providing more accurate, timely, and individualised information. By detecting specific biomarkers accurately, we can tailor treatments to the unique needs of each patient, potentially improving outcomes and enhancing the quality of care.
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