WASHINGTON - A fourth dose of existing mRNA Covid-19 vaccines may have only"marginal benefits" for younger, healthy adults, according to a new Israeli study published Wednesday in the New England Journal of Medicine.
Overall, the fourth shot was found to be safe, and topped up recipients' neutralising antibodies - which block the coronavirus from infecting cells - to levels comparable to just after the third dose, prior to when antibody levels started waning with time. Protection against symptomatic infection was slightly better in under-40 adult recipients of a fourth jab - 43 per cent for Pfizer and 31 per cent for Moderna - compared to people who received three shots.
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