Elderly Should Consider Booster Doses of Covid-19 Vaccine, Study Finds

An NUS Yong Loo Lin School of Medicine study found that people aged 65 and above continued to get infected with Covid-19 despite having received the first two jabs.

The study was led by Dr Vanda Ho, a PhD student at the Department of Microbiology and Immunology, and Immunology and Infectious Diseases Translational Research Programmes at NUS Yong Loo Lin School of Medicine. mRNA vaccines work by introducing a small piece of a protein found in the virus so that cells can produce the viral protein. The immune system then recognises the protein as foreign and produces antibodies to protect the body against infection.

“Unfortunately, after that first infection, they tend to be re-admitted for further infections. I saw the same patients decline functionally and cognitively because of the initial infection. Dr Ho said that immune cells play a key role in helping to produce antibodies that neutralise potential viral infection, but the immune cell count is lower in older adults.

“From my study, older adults have a relative deficiency in a specific immune T cell type, and this correlates with the smaller neutralisation activity in older adults when the cells are exposed to the virus parts in the lab,” Dr Ho said.

Source: Education Headlines (educationheadlines.net)

Elderly Booster Doses Covid-19 Vaccine Study NUS Yong Loo Lin School Of Medicine

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