Vaccine trials 'can't detect' virus risk reduction: expert

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None of the trials of Covid-19 candidate vaccines can detect a reduction in serious outcomes such as hospitalisation or death, a leading public health

"Nor are the vaccines being studied to determine whether they can interrupt transmission of the virus.", ten of which are in the most advanced"phase 3" stage.'s effectiveness is tested on a large scale, generally tens of thousands of people across several continents.

But Doshi, assistant professor of pharmaceutical health services research at the University of Maryland School of Pharmacy, said that even the most advancedThis may be down to the numbers of people involved in , he said, pointing out that the majority of confirmed Covid-19 infections involve mild or no symptoms. are designed to find out whether there is a benefit among the elderly, a key at-risk constituency. in sufficient numbers, Doshi said"there can be little basis for assuming any benefit against hospitalisation or mortality. , making it unlikely that the experiments will address key gaps in our understanding of how Covid-19 develops differently among individuals.

 

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