Pfizer, BioNTech say Omicron-based COVID shots improve response vs that variant

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The shots are well-tolerated in participants, the companies say.

NEW YORK, USA – Pfizer and BioNTech SE said on Saturday, June 25, that a booster dose of updated versions of their COVID-19 vaccine, modified specifically to combat the Omicron coronavirus variant, generated a higher immune response against that variant.

Pfizer and BioNTech said that 30 and 60 microgram doses of a shot targeting just the BA.1 Omicron subvariant that was circulating last winter elicited a 13.5 and 19.6-fold increase in neutralizing geometric titers against that subvariant. A version of the shot that contained both the redesigned vaccine and their original vaccine elicited a 9.1 and 10.9-fold increase, they said.

 

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