. “An ideal Covid-19 vaccine should reduce upper respiratory tract virus replication and block transmission as well as protect against severe disease.” , researchers from the University of Alabama at Birmingham are also advocating the benefits of nasal spray. According to them, it could even be more effective, since “immunoglobulin A and resident memory B and T cells in the nasal passages and upper airways are elicited by intranasal vaccination and prevent infection and reduce virus shedding.
In France, researchers at the University of Tours are also working on a nasally-administered vaccine. The 20 or so researchers who have been working on the project since last summer hope to start testing the vaccine on humans at the end of 2021, or early in 2022. A total of six nasal spray vaccine projects are being studied worldwide. This method of administration is still relatively unusual for vaccines, even though it has been used in certain countries, like the United States, for flu vaccines. Other solutions are being explored to facilitate the use of Covid-19 vaccines around the world. In a global first, a clinical trial for an orally administered vaccine has just been launched in Israel, according to the.
For the moment, this orally administered vaccine has shown its effectiveness in several animal trials, even against the Delta variant. If commercialised, it is likely to be used primarily in developing countries, where vaccination rates are low due to the logistical challenges of using currently available vaccines. — ETX Studio
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