looking at mixing Covid-19 vaccines showed that receiving a booster shot of CanSino Biologics' vaccine after one or two doses of Sinovac Biotech's vaccine yielded a much stronger antibody response than using the Sinovac shot as a booster.
Participants who received a CanSinoBIO booster dose three to six months after a second Sinovac shot showed a 78-fold jump on average in neutralising antibody levels two weeks later, according to a paper published yesterday before a peer review. One dose of Sinovac followed by a CanSinoBIO booster at intervals of one or two months led to a 25.7-fold increase in neutralising antibody levels, while two doses of Sinovac induced a 6.2-fold increase.The study did not assess the boosters' protection against Covid-19 and did not test the neutralising antibody against the more transmissible Delta variant, the paper said.
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