Race for vaccine tests limits of drug innovation | Malay Mail

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GENEVA, April 1 — From medical workers struggling to care for the rising tide of Covid-19 patients to the billions of people told to stay home to slow the pandemic, everyone is waiting for one thing: a vaccine. There is no known treatment for the new coronavirus that emerged in China late last...

The traditional method for developing vaccines has been to introduce a modified part of the infectious agent to stimulate the body's immune system without doing harm. — JurgaR/Istock.com

The approaches have varied dramatically. Some teams are looking at the effects of existing medicines as potential treatments, some are experimenting with repurposing common drugs. Others are using cutting-edge technologies to fashion radically new types of vaccines. While the world will try to “squeeze it down dramatically,” the timeline will still depend on the testing process.

The Coalition for Epidemic Preparedness Innovations , a global organisation based in Oslo, has called for US$2 billion to support the development of a vaccine. This replica itself is now the basis for a vaccine candidate. NIH is working with Moderna, a relatively new firm founded in 2010, to make a vaccine using the protein's genetic information to grow it inside human muscle tissue, rather than having to inject it in.

These are the experimental antiviral treatment remdesivir; a combination of two HIV drugs, lopinavir and ritonavir; those two drugs plus interferon beta, an immune system medication; and the malaria drug chloroquine. Benjamin Neuman, a virologist at Texas A&M University-Texarkana, told AFP that when viruses copy themselves, they do it “quickly and a bit sloppily,” meaning they might incorporate remdevisir into their structure — though human cells, which are more fastidious, won't make the same mistake.

 

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