Breast cancer drug shown to reduce recurrence risk

Novartis plans to submit its data to regulatory authorities in the US and Europe by this year.

Results from a clinical trial were presented todat at the American Society of Clinical Oncology’s annual meeting. “The current standard of therapy for these patients is surgery followed by chemotherapy… or radiation, then followed by between five and 10 years of hormonal blockade by various endocrine therapies,” lead author Dennis Slamon of the UCLA Jonsson Comprehensive Cancer Center told reporters.

The clinical trial involved more than 5,100 people with stage II and stage III forms of HR-positive, HER2-negative breast cancer, which is the most common subtype, making up nearly 70% of all breast cancer cases in the US. Overall, 7.4% of patients in the ribociclib group experienced a recurrence against 9.2% of patients in the hormone therapy-only group, which means an approximate risk reduction of 25%.

“Addressing this unmet need across such a broad patient population could help streamline treatment decisions for healthcare providers and keep many more at-risk patients cancer-free without disrupting their daily lives,” said Slamon in a statement.

Source: Healthcare Press (healthcarepress.net)

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