Scientists find 57,000 cells and 150m neural connections in tiny sample of human brain

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Harvard researchers teamed up with Google to analyse the makeup of the brain, much of which is not yet understood

Scientists have reconstructed a wiring diagram for a piece of human brain in unprecedented detail, revealing fresh quirks and complexities in what many regard as the most sophisticated object in the known universe.to map out the neural circuitry, connections, supporting cells and blood supply in a speck of healthy tissue removed from the cortex of a 45-year-old woman who had had surgery for epilepsy.

The sample, which measured a cubic millimetre in size, was taken from the brain of a 45-year-old woman who had had surgery.“The aim was to get a high resolution view of this most mysterious piece of biology that each of us carries around on our shoulders,” said Jeff Lichtman, a professor of molecular and cellular biology at Harvard. “The reason we haven’t done it before is that it is damn challenging. It really was enormously hard to do this.

“We found many things in this dataset that are not in the textbooks,” said Lichtman. “We don’t understand those things, but I can tell you they suggest there’s a chasm between what we already know and what we need to know.”

 

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