Breaking the wave: What will it take for us to get ahead of COVID-19?

. But experts say it isn’t feasible to create altered vaccines for every new variant.

“So far we’ve got a number of antibodies that bind to a huge selection of coronaviruses,” says Dooley. “So it does look like this vaccine is, at least in our animals, raising antibodies that might be able to protect against the other variants, and maybe future variants.” Until one of these “pan-variant” vaccines are widely available we’ll be “chasing the virus” as it mutates, says Professor Nicholas Wood, senior staff specialist at the National Centre for Immunisation Research and Surveillance .

“All of the sub-variants now that we’re getting with Omicron are coming along so quickly,” she says from her office at the Charles Perkins centre at the University of Sydney. “Having to re-engineer a vaccine every time a new variant comes along is very challenging. And by the time you’ve done that the next wave is coming from a different variant.

Once a spike protein is identified the project will use the “protein-subunit” method to make a vaccine. DNA that codes for the spike protein is inserted into a carrier molecule called a “plasmid”. The molecule delivers the DNA into mammalian cells, which are used as a factory to produce the spike proteins. The proteins are collected, purified, and combined with an adjuvant - a substance that triggers an immune response - to create the resulting vaccine.

“It’s just hard to get a response that’s sufficient to stop the virus getting in and infecting people,” says University of Queensland infectious diseases physician Dr Paul Griffin. A nasal vaccine called FluMist is already used in the US as an alternative to influenza shots. And he says there’s “lots to be excited by” in the pipeline.

angus_dalton the spreaders could be given an incentive to stay home......?

angus_dalton You’ve followed the script perfectly. Complete diarrhoea. How about reporting on the failure and damage of these disgusting injections.

angus_dalton Responsible political health policy and action 2.5 years ago. Sadly we had Scomo and Murdoch misinformation instead.

angus_dalton How about getting on with life and stop going on and on about it

angus_dalton Question: what will it take for us to get ahead of COVID-19? Answer: “Vaccines are our only way out of the pandemic.” 🤦🏻‍♂️🤦🏻‍♂️🤦🏻‍♂️ We will never ‘get ahead of it’ if you refuse to report on available measures which work. As such, more people will die and face disablement.

angus_dalton Will you finally come out and say that you know full well the rushed to market vax is simply not working? Come on, you're thinking it aren't you? But your such a spineless, cowardly lot at SMH & The Age to ever go outside the Overton Window of discussion on this topic.

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