We Could Use Ultrasound to Command Bacteria to Nuke Tumors

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Focused ultrasound is about to get a big boost from an unlikely ally: bacteria

bacteria to kill cancer after being activated by ultrasound-induced heat—laying any harm to surrounding healthy cells. These bacteria not only prevented tumors in mice from growing larger, they also managed to cut down a tumor’s size outright. The findings may help clinicians develop a more targeted search-and-destroy method for combating cancer, and might also be adapted later on into helping fight off other infections localized to a specific part of the body.

Over the years, scientists sought to exploit this bizarre relationship by having bacteria deliver chemotherapy payloads directly to cancer cells. But they ran the risk of harming healthy cells that might cross the bacteria’s path.Shapiro and his team thought they could get around this problem by finding a way to remote control bacteria to nuke cancer cells on command.

 

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