Highly effective weight-loss drug Zepbound approved in the US and UK

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Highly effective weight-loss drug Zepbound approved in the US and UK
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A drug called tirzepatide and sold under the name Zepbound has been approved in the US and the UK for use as a weight-loss medication

A weight-loss drug called tirzepatide has received approval from the US Food and Drug Administration for adults who are overweight or have obesity and at least one weight-related condition, such as high blood pressure or type 2 diabetes. It has also been approved by the, although it is unlikely to be used by National Health Service doctors unless it also gets approved as cost-effective in a separate assessment.

In clinical trials, tirzepatide reduced body weight by an average of almost 21 per cent in people who were overweight or had obesity. “That’s the most weight loss we’ve ever seen with a medication,” saysA type of vitamin B3 might treat chronic pain related to inflammation “With rising rates of obesity, there’s been an increased demand for medications indicated for weight management, and we have faced shortages in the past,” saysTirzepatide, sold under the brand name Zepbound, is a once-weekly injection that mimics two hormones: GLP-1 and GIP. The body naturally produces GIP once we start eating, which increases hunger, and then releases GLP-1 after eating to trigger the sensation of fullness, says Aronne.

For many people with obesity, the health benefits of tirzepatide outweigh its potential downsides. “One of the best outcomes can be reversing complications that are associated with ,” says Jaisinghani. “By reversing some of those complications we now have an opportunity to potentially take people off other medications, and this not only improves their health, but their quality of life.”

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