💥 CSF MTBR-tau243 is an accurate biomarker of aggregated tau and clinical cognitive impairment in Alzheimers disease, with higher specificity than current phospho-tau biomarkers. AD OskarHansson9 gesalbla biofinder_study KantaHorie
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.Levels of each CSF biomarkers by clinical diagnosis and amyloid status in the BioFINDER-2 cohort . Amyloid-positive participants were selected based on CSF Aβ42/40 . *, p < 0.050; **, p < 0.010; ***, p < 0.001.
In BioFINDER-2 cohort , orange dots represent MCI+ participants whereas in the Kinght-ADRC cohort , represent very mild AD. Linear regression models, adjusting for age, sex and years of education were used to obtain standardized β and p-values shown in the plots. *, p < 0.50; **, p < 0.010; ***, p <0.001.
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