One of the most fascinating discoveries in biology is that cells have mechanisms for dynamically regulating genetic expression.
Nara Institute of Science and Technology Sep 11 2024 This ability to promote or restrict the transcription of specific genes without altering the DNA sequences themselves is essential to all forms of life, from single-cell organisms to the most complex plants and animal species.
In a recent study published in eLife, a research team from Nara Institute of Science and Technology in Japan sought to find answers to this puzzle. Led by Nobutoshi Yamaguchi, the team conducted extensive experiments on genetically modified Arabidopsis thaliana plants, revealing key parts of the complex epigenetic orchestra that goes on within these and many other organisms.
After an extensive series of analyses and measurements on mutant A. Thaliana cultures, the researchers uncovered a new role for SDG7. It turns out this protein also binds to PREs, competing with PRC2. Moreover, SDG7 can actually displace PRC2, preventing it from leaving the H3K27me3 mark. On top of this, SDG7 adds an active histone mark itself via the methylation of H3K36.
Cell DNA Genes Genetic Histones Protein Research Technology Transcription
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Celtic transfer bulletin as Engels 'tells friends' he wants Parkhead moveThe latest from Parkhead on one in, one out, and one who has already arrived
Read more »
Knocking out one key gene leads to autistic traits, mouse study showsMore than 70 genes have been linked to autism spectrum disorder (ASD), a developmental condition in which differences in the brain lead to a host of altered behaviors, including issues with language, social communication, hyperactivity, and repetitive movements.
Read more »
Eating one type of meal reduces depression in men, study findsDoctors should send tens of thousands of unhappy young men to a dietitian as part of their treatment programme, a study has found
Read more »
Study finds nearly half of US counties have at least one 'pharmacy desert'Nearly half of counties in the United States have at least one 'pharmacy desert' where there is no retail pharmacy within 10 miles, according to a study published in JAMA Network Open by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James).
Read more »
Quitting one vice slashes heart attack risk by nearly half, study findsNew research has found that patients with stable coronary artery disease who quit smoking drastically reduced their risk of a major cardiac event
Read more »
Two-in-one treatment could hold promise for incurable brain cancer, mouse study showsResearchers at WEHI have identified a promising new two-in-one treatment that not only targets and destroys an aggressive form of brain cancer, but also helps the immune system develop a lasting defense against it.
Read more »