Could mind games help treat teen depression? Brain imaging study shows promise northeastern MolPsychiatry
\{{{{{\rm{activation}}}}}}\;{{{{{\rm{estimate}}}}}}} - \widetilde {{{{{{\rm{NOI}}}}}}{{{{{\rm{activation}}}}}}\;{{{{{\rm{estimate}}}}}}}\)
. This PDA metric is based on the hypothesis that there is a causal neural mechanism by which the CEN downregulates the DMN [-value from the previous TR and the updated-value was rendered as the new position of the white dot. Visually, the white dot would move upwards with positive PDA values and downwards with negative PDA values. The time delay between collection of a complete EPI volume and its associated position update was 30.5 s, and the position updated every TR.
During mbNF, participants were instructed to practice mindfulness to move the white dot on the screen up into the red circle. The movement of the white dot was dependent on a real-time analysis of the fMRI data that computed the difference in personalized DMN and CEN activations. When DMN activation is lower than CEN activation, the white dot moves up; when DMN activation is higher than CEN activation, the white dot moves down.There were five back-to-back neurofeedback runs .
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