Women with atrial fibrillation (AF) undergoing a procedure called pulsed field ablation (PFA) have just as good outcomes as men with AF undergoing the same procedure, according to a large-scale international study led by the Icahn School of Medicine at Mount Sinai.
This study is the first to compare sex outcomes for AF patients undergoing PFA, which is a new technology and the latest ablation modality that can be used to restore a regular heartbeat. The results also show PFA is safe and just as effective for men as for women. Findings were published October 5 in JAMA Cardiology.
Two types of ablation are currently in common use: radiofrequency ablation, which uses heat energy to eliminate the problem area, and cryoablation, which uses cold energy. These ablation modalities are associated with increased risk of potential complications, including damage to the esophagus, pulmonary vein stenosis, and phrenic nerve injury. PFA is a new type of ablation that does not use temperature, but instead short, high-energy electrical pulses that target mainly cardiac cells.
The results showed no significant difference in recurring atrial arrhythmia in men versus women. Specifically, 79 percent of men versus 76 percent of women did not have recurring atrial arrhythmia after PFA, a difference that was not statically significant. The rate of patients needing a second ablation were similar between sexes, with men at 8.3 percent versus women at 10 percent, also not statically significant.
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Study shows women with atrial fibrillation significantly benefit from pulsed field ablation proceduresWomen with atrial fibrillation (AF) undergoing a procedure called pulsed field ablation (PFA) have just as good outcomes as men with AF undergoing the same procedure, according to a large-scale international study led by the Icahn School of Medicine at Mount Sinai.
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