“Congenital leukemia refers to the rare condition of cancer that is present at birth and clinical signs appear within the first 4 weeks. Congenital Leukemia is found different from childhood leukemia which evolves later in a child’s life.
The exact causes of congenital leukemia are not known, but it has been linked with maternal exposure to radiation, maternal dietary exposure to bioflavonoid, maternal use of tobacco and illicit drugs and inherited conditions such as Down’s syndrome, neurofibromatosis, Bloom’s syndrome, and Fanconi’s anemia. KMTA2A gene mutations may be other risk factors for this rare kind of leukemia.
The diagnosis of children with signs or symptoms of leukemia can be done through physical exam, blood tests, imaging tests such as CT and MRI scans, lumbar puncture, or spinal tap, bone marrow aspiration and biopsy.
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