Wanted: Volunteers to catch Covid-19 in the name of science

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The world's first medical trial authorised to deliberately expose participants to the coronavirus is seeking more volunteers as it steps up efforts to help develop better vaccines. The Oxford University trial was launched last April, three months after Britain became the first country to approve what are known as challenge trials for humans involving Covid-19. Its first phase, still ongoing,...

The world's first medical trial authorised to deliberately expose participants to the coronavirus is seeking more volunteers as it steps up efforts to help develop better vaccines.

They then plan to expose volunteers - all previously naturally infected or vaccinated - to that dose of the virus's original variant to determine what levels of antibodies or immune T-cells are required to prevent an infection. Global immunologists have been seeking to pinpoint the immune reaction that a vaccine must produce to shield against the illness, known as a correlate of protection. Once discovered, the need for mass vaccine trials is greatly reduced.

 

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