A new variant of SARS-CoV-2, the virus which cause Covid-19, has been detected in South Africa and many other countries. It has been identified as the potential variant of interest that is assigned to the PANGO lineage C.1.2.Scientists from National Institute for Communicable Diseases and the KwaZulu-Natal Research Innovation and Sequencing Platform in South Africa said the potential variant of interest, C.1.2, was first detected in the country in May this year.
According to the study, C.1.2 lineage has a mutation rate of about 41.8 mutations per year, which is about twice as fast as the current global mutation rate of the other variants.The spike protein is used by the SARS-CoV-2 virus to infect and enter human cells, and most vaccines target this region. The mutations N440K and Y449H, which have been associated with immune escape from certain antibodies, have also been noticed in C.1.2 sequences.
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