Some Children With COVID-Related Syndrome Develop Neurological Symptoms

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The study of 46 children treated at one hospital in London for COVID-19 found that just over half experienced such neurological symptoms, which they had never had before.

A photo provided by LaRovere et al., JAMA Neurolology 2021 shows CT scans of the brain of a previously healthy toddler with Multisystem Inflammatory Syndrome, top; and those of a school-aged child with the condition, bottom, from a study published last month in JAMA Neurology.

Those patients were about twice as likely as those without neurological symptoms to need ventilators because they were “very unwell with systemic shock as part of their hyperinflammatory state,” said an author of the study, Dr. Omar Abdel-Mannan, a clinical research fellow at University College London’s Institute of Neurology. Patients with neurological symptoms were also about twice as likely to require medication to improve the heart’s ability to squeeze, he said.

As was the case with other studies of the syndrome, including in the United States, the researchers said a majority of those afflicted were “nonwhite,” a pattern that public health experts believe reflects the disproportionate way the pandemic has affected communities of color. Nearly two-thirds of the patients were male, and the median age was 10.

Some of the patients underwent brain scans, nerve conduction tests or electroencephalograms , including 14 who showed slower electrical activity in their brains, the study reported.

 

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