Monoclonal antibodies are immune system proteins that are created in the laboratory and can be specially designed and engineered to target Sars-CoV-2.
Half of the 500 patients will receive a placebo in the double-blind trial so that the drug's effectiveness can be tested, said Prof Ooi. Tychan will work with hospitals under SingHealth to recruit the patients.The recruitment process has not started yet because the final trial is pending approval from the authorities.
Clinical trials are commonly conducted in four phases, beginning with a small group to test the drug's safety and side effects, then moving on to larger groups to determine its efficacy. TY027 is being explored for the treatment of Covid-19 patients in slowing the progression of the disease and speeding up recovery, as well as potentially providing temporary protection against infection.
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