Covid-19 booster efficacy wanes significantly by fourth month: US study

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WASHINGTON - The efficacy of third doses of the Pfizer and Moderna mRNA vaccines wanes substantially by the fourth month after administration, a new study by the US Centres of Disease Control and Pre

vention said on Friday .

The new study was based on more than 241,204 visits to the emergency department or an urgent care clinic, and 93,408 hospitalisations, which are more serious, among adults with Covid-19-like illness during August 26, 2021-January 22, 2022. During the Omicron-predominant period, vaccine efficacy against Covid-associated emergency department or urgent care visits was 87 per cent during the two months after a third dose, but fell to 66 per cent by the fourth month.

"The finding that protection conferred by mRNA vaccines waned in the months after receipt of a third vaccine dose reinforces the importance of further consideration of additional doses to sustain or improve protection," the authors concluded.

 

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