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“There’s not enough evidence right now to support that that is somehow the best use of resources,” said Natalie Dean, a biostatician at Emory University in Atlanta.Still, the findings raise questions about how well the Pfizer vaccine will prevent infection in the months to come. And with coronavirus cases surging again in many states, the data may influence the Biden administration’s deliberations about delivering boosters for older people.
“Everything that’s engaged by the vaccine is able to fight off that spread that ultimately leads to severe disease,” Iwasaki said. “That’s probably not declining at all.” In other words, the risk of getting sick was reduced by 95% in the group that got the vaccine, compared with the group that got the placebo. That result — the first for any COVID-19 vaccine — brought an exhilarating dose of hope to the world in December when it was riding what had been the biggest wave of the pandemic.
Those figures still describe a remarkably effective vaccine, however, and may not convince critics that booster shots are widely needed.
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