Widowhood increases risk of Alzheimer's, study says

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Alzheimer's strikes many more women than men, and the study authors suggest widowhood may explain some of that discrepancy between the sexes

Losing your spouse or life partner and gaining the designation"widow" or"widower" is one of life's cruelest blows.

Even for those without beta-amyloid accumulation and no signs of cognitive decline, the risk for dementia was greater for men and women who were widowed. "This is a very important study," said Dr. Richard Isaacson, who directs the Alzheimer's Prevention Clinic at Weill Cornell Medicine in New York City.

Previous research has shown that becoming a widow, especially later in life, is associated with memory problems, cognitive decline and dementia. There was no difference in brain functioning between married and unmarried groups. However, widowed adults showed more cognitive decline than the married/unmarried groups, regardless of age, sex, socioeconomic status or depression. The decline was three times as fast for those with existing beta-amyloid plaques.

 

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